



Our Passion
At NANISX, our passion is deeply anchored in transforming the landscape of outpatient spine surgery for orthopedic surgeons, neurosurgeons and interventional pain management.

Our Company
NANISX was founded under KIC Ventures to build a new specialty: Interventional Spine Surgery. We began with a revolutionary belief: interventional pain physicians should not just modulate pain — they should correct its source. For decades, spine care relied on injections, medications, radiofrequency ablation, and spinal cord stimulation to mask symptoms. We saw a different future. We studied how cardiologists transformed into interventional cardiologists — replacing open chest surgery with image-guided, percutaneous techniques that preserved anatomy, enabled earlier intervention, and restored function. From that transformation, we developed our own proprietary philosophy: Less Exposure Spine Surgery (LESS™) and REP™ — Restore Function, Early Diagnosis and Treatment, Preserve Anatomy and Spinal Motion. By combining the precision of minimally invasive spine surgery (MISS) with the percutaneous discipline of interventional pain management, we established a new procedural standard rooted in LESS™ and REP™ principles. We were the first to train interventional pain physicians to perform lumbar decompression and instrumented fusion using a midline approach with InSpan — avoiding pedicle screws and interbody cages while preserving anatomy and motion. We tracked outcomes. Patients improved. Physicians performed the procedures safely and reproducibly under our structured protocols and mentorship. We published peer-reviewed research validating safety and advancing technique. When early SI joint grafting methods led to dislodgement, we engineered a better solution: Sacrix — the first multi-threaded triangular transfixation screw with self-harvesting capability and large graft windows. We trained physicians in a posterior lateral to oblique fixation approach and published a landmark study on the cover of the NASS Spine Journal demonstrating that interventional physicians can safely perform decompression, spinal fusion, and SI joint fusion. We continue expanding the NANISX portfolio, including the launch of ELID, because Interventional Spine Surgery must span the full continuum of care — from injection to fusion. Through our VET Tour at our Fort Lauderdale headquarters, we have trained more than 500 interventional pain physicians and over 1,000 spine surgeons. In partnership with the LESS Society, we established the Interventional Spine Surgery certification program with rigorous standards and accountability. This is not incremental change. This is the formalization of a new specialty. And we are building it.
